Please use this identifier to cite or link to this item: https://biore.bio.bg.ac.rs/handle/123456789/7169
Title: Potential application of green extracts rich in phenolics for innovative functional foods: natural deep eutectic solvents as media for isolation of biocompounds from berries
Authors: Lazović, Mila Č.
Jović, Marko D.
Petrović, Marija
Dimkić, Ivica Z. 
Gašić, Uroš M.
Milojković Opsenica, Dušanka M.
Ristivojević, Petar M.
Trifković, Jelena Đ.
Issue Date: 2024
Rank: M21
Publisher: Royal Society of Chemistry
Journal: Food & Function
Volume: 15
Issue: 8
Start page: 4122
End page: 4139
Abstract: 
The health-promoting effects of berries have attracted attention due to the possible application of their extracts as functional ingredients in food products. Natural deep eutectic solvents (NADESs) are a new generation of environmentally friendly solvents for the extraction of natural products, and they are green alternatives to organic solvents, and they can improve the solubility, stability, and bioavailability of isolated biocompounds. In this study, an efficient eco-friendly method was used for the extraction of phenolic compounds from different berries: chokeberries, blueberries, and black goji berries with a range of eutectic solvents consisting of hydrogen bond acceptors (HBAs) such as choline chloride, L-proline, L-glycine, and L-lysine and hydrogen bond donors (HBDs) such as malic, citric, tartaric, lactic and succinic acids, glucose and glycerol. The obtained results indicated the ability of NADESs towards selective extraction of phenolics; the eutectic system choline chloride : malic acid showed selective extraction of anthocyanins, while choline chloride : glycerol and choline chloride : urea showed selectivity towards flavonoids and phenolic acids. The methodology for screening of the NADES extraction performance, which included chromatographic profiling via high-performance thin layer chromatography combined with chemometrics and spectrophotometric essays, allowed effective assessment of optimal eutectic solvents for isolation of different groups of phenolics. Great antioxidant and antimicrobial activities of extracts, along with the green nature of eutectic solvents, enable NADES berry extracts to be used as “green-labelled” functional foods or ingredients.
URI: https://biore.bio.bg.ac.rs/handle/123456789/7169
ISSN: 2042-6496
2042-650X
DOI: 10.1039/D3FO05292C
Appears in Collections:Journal Article

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