Please use this identifier to cite or link to this item: https://biore.bio.bg.ac.rs/handle/123456789/6757
Title: SecReT6 update: a comprehensive resource of bacterial Type VI Secretion Systems
Authors: Zhang, Jianfeng
Guan, Jiahao
Wang, Meng
Li, Gang
Đorđević, Marko 
Tai, Cui
Wang, Hui
Deng, Zixin
Chen, Zhaoyan
Ou, Hong-Yu
Keywords: Acinetobacter baumannii;T6SS-related protein;Type VI Secretion System;database;prediction
Issue Date: Mar-2023
Rank: M21a
Journal: Science China. Life sciences
Volume: 66
Issue: 3
Start page: 626
End page: 634
Abstract: 
Type VI Secretion System (T6SS) plays significant roles in microbial activities via injecting effectors into adjacent cells or environments. T6SS increasingly gained attention due to its important influence on pathogenesis, microbial competition, etc. T6SS-associated research is explosively expanding on numerous grounds that call for an efficient resource. The SecReT6 version 3 provides comprehensive information on T6SS and the interactions between T6SS and T6SS-related proteins such as T6SS regulators and T6SS effectors. To assist T6SS researches like microbial competition and regulatory mechanisms, SecReT6 v3 developed online tools for detection and analysis of T6SS and T6SS-related proteins and estimation of T6SS-dependent killing risk. We have identified a novel T6SS regulator and T6SS-dependent killing capacity in Acinetobacter baumannii clinical isolates with the aid of SecReT6 v3. 17,212 T6SSs and plentiful T6SS-related proteins in 26,573 bacterial complete genomes were also detected, analyzed and incorporated into the database. The database is freely available at https://bioinfo-mml.sjtu.edu.cn/SecReT6/ .
URI: https://biore.bio.bg.ac.rs/handle/123456789/6757
ISSN: 16747305
DOI: 10.1007/s11427-022-2172-x
Appears in Collections:Journal Article

Show full item record

SCOPUSTM   
Citations

21
checked on Nov 4, 2024

Page view(s)

2
checked on Nov 4, 2024

Google ScholarTM

Check

Altmetric

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.