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Title: | Fluoride subacute testicular toxicity in Wistar rats: Benchmark dose analysis for the redox parameters, essential elements and DNA damage |
Authors: | Radovanović, Jelena Antonijević, Biljana Ćurčić, Marijana Baralić, Katarina Kolarević, Stoimir Bulat, Zorica Đukić-Ćosić, Danijela Buha Djordjević, Aleksandra Vuković-Gačić, Branka Javorac, Dragana Antonijević Miljaković, Evica Carević, Momir Mandinić, Zoran |
Keywords: | Benchmark methodology;Bioelements;Comet assay;Fluoride;Oxidative stress;Testicles |
Issue Date: | 1-Dec-2022 |
Rank: | M21 |
Publisher: | Elsevier Ltd |
Journal: | Environmental Pollution |
Abstract: | Excessive fluoride (F-) levels in the environment could induce different pathological changes, including comorbidities in reproductive functions. Hence, the aim of the present in vivo study was to explore F- subacute toxicity mechanisms via Benchmark dose (BMD) methodology on rat's testicles. The experiment was conducted on thirty male Wistar rats for 28 days, divided into six groups (n = 5): 1) C... |
URI: | https://biore.bio.bg.ac.rs/handle/123456789/4705 |
DOI: | 10.1016/j.envpol.2022.120321. |
Appears in Collections: | Journal Article |
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