Please use this identifier to cite or link to this item:
https://biore.bio.bg.ac.rs/handle/123456789/1544
Title: | Trametes versicolor ethanol extract, a promising candidate for health–promoting food supplement | Authors: | Janjušević, Ljiljana Pejin, Boris Kaišarević, Sonja Gorjanović, Stanislava Pastor, Ferenc Tešanović, Kristina Karaman, Maja |
Keywords: | antioxidant activity;antiradical activity;cytotoxic activity;ethanol extract;hydroxybenzoic acids;Trametes versicolor | Issue Date: | 18-Apr-2018 | Rank: | M22 | Journal: | Natural Product Research | Abstract: | © 2017 Informa UK Limited, trading as Taylor & Francis Group. This study aimed to estimate antiradical, antioxidant (AO) and cytotoxic activities of the fungus Trametes versicolor ethanol fruiting body extract. The extract was found to effectively scavenge both O2•− and NO• (29.62 and 52.48 μg/mL, respectively). It also showed a good AO activity in the polarographic HPMC assay (950%/mL). p-Hydroxybenzoic acid may be one of the responsible compounds for the afore-mentioned activities. The same extract also exhibited a concentration-dependent cytotoxicity against MCF-7 and HepG2 tumour cell lines reaching IC50 values of 123.51 and 134.29 μg/mL, respectively with no cytotoxic activity against normal MRC-5 cells. Gentisic, syringic and protocatechuic acids may be among the bioactive principles for the observed cytotoxicity. Taken all together, T. versicolor ethanol extract can be considered as a promising candidate for development of health promoting food supplement. |
URI: | https://biore.bio.bg.ac.rs/handle/123456789/1544 | ISSN: | 1478-6419 | DOI: | 10.1080/14786419.2017.1366484 |
Appears in Collections: | Journal Article |
Files in This Item:
File | Description | Size | Format | Existing users please |
---|---|---|---|---|
Trametes versicolor ethanol extract, a promising.pdf | 764.18 kB | Adobe PDF | Request a copy |
SCOPUSTM
Citations
21
checked on Nov 16, 2024
Page view(s)
2
checked on Nov 20, 2024
Google ScholarTM
Check
Altmetric
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.