Please use this identifier to cite or link to this item: https://biore.bio.bg.ac.rs/handle/123456789/1544
Title: Trametes versicolor ethanol extract, a promising candidate for health–promoting food supplement
Authors: Janjušević, Ljiljana
Pejin, Boris
Kaišarević, Sonja
Gorjanović, Stanislava
Pastor, Ferenc
Tešanović, Kristina 
Karaman, Maja
Keywords: antioxidant activity;antiradical activity;cytotoxic activity;ethanol extract;hydroxybenzoic acids;Trametes versicolor
Issue Date: 18-Apr-2018
Rank: M22
Journal: Natural Product Research
Abstract: 
© 2017 Informa UK Limited, trading as Taylor & Francis Group. This study aimed to estimate antiradical, antioxidant (AO) and cytotoxic activities of the fungus Trametes versicolor ethanol fruiting body extract. The extract was found to effectively scavenge both O2•− and NO• (29.62 and 52.48 μg/mL, respectively). It also showed a good AO activity in the polarographic HPMC assay (950%/mL). p-Hydroxybenzoic acid may be one of the responsible compounds for the afore-mentioned activities. The same extract also exhibited a concentration-dependent cytotoxicity against MCF-7 and HepG2 tumour cell lines reaching IC50 values of 123.51 and 134.29 μg/mL, respectively with no cytotoxic activity against normal MRC-5 cells. Gentisic, syringic and protocatechuic acids may be among the bioactive principles for the observed cytotoxicity. Taken all together, T. versicolor ethanol extract can be considered as a promising candidate for development of health promoting food supplement.
URI: https://biore.bio.bg.ac.rs/handle/123456789/1544
ISSN: 1478-6419
DOI: 10.1080/14786419.2017.1366484
Appears in Collections:Journal Article

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