Please use this identifier to cite or link to this item: https://biore.bio.bg.ac.rs/handle/123456789/1544
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dc.contributor.authorJanjušević, Ljiljanaen_US
dc.contributor.authorPejin, Borisen_US
dc.contributor.authorKaišarević, Sonjaen_US
dc.contributor.authorGorjanović, Stanislavaen_US
dc.contributor.authorPastor, Ferencen_US
dc.contributor.authorTešanović, Kristinaen_US
dc.contributor.authorKaraman, Majaen_US
dc.date.accessioned2019-10-08T11:39:48Z-
dc.date.available2019-10-08T11:39:48Z-
dc.date.issued2018-04-18-
dc.identifier.issn1478-6419-
dc.identifier.urihttps://biore.bio.bg.ac.rs/handle/123456789/1544-
dc.description.abstract© 2017 Informa UK Limited, trading as Taylor & Francis Group. This study aimed to estimate antiradical, antioxidant (AO) and cytotoxic activities of the fungus Trametes versicolor ethanol fruiting body extract. The extract was found to effectively scavenge both O2•− and NO• (29.62 and 52.48 μg/mL, respectively). It also showed a good AO activity in the polarographic HPMC assay (950%/mL). p-Hydroxybenzoic acid may be one of the responsible compounds for the afore-mentioned activities. The same extract also exhibited a concentration-dependent cytotoxicity against MCF-7 and HepG2 tumour cell lines reaching IC50 values of 123.51 and 134.29 μg/mL, respectively with no cytotoxic activity against normal MRC-5 cells. Gentisic, syringic and protocatechuic acids may be among the bioactive principles for the observed cytotoxicity. Taken all together, T. versicolor ethanol extract can be considered as a promising candidate for development of health promoting food supplement.en_US
dc.language.isoenen_US
dc.relation.ispartofNatural Product Researchen_US
dc.subjectantioxidant activityen_US
dc.subjectantiradical activityen_US
dc.subjectcytotoxic activityen_US
dc.subjectethanol extracten_US
dc.subjecthydroxybenzoic acidsen_US
dc.subjectTrametes versicoloren_US
dc.titleTrametes versicolor ethanol extract, a promising candidate for health–promoting food supplementen_US
dc.typeArticleen_US
dc.identifier.doi10.1080/14786419.2017.1366484-
dc.identifier.pmid28817965-
dc.identifier.scopus2-s2.0-85027868180-
dc.identifier.urlhttps://api.elsevier.com/content/abstract/scopus_id/85027868180-
dc.description.rankM22-
dc.description.impact2.861-
item.languageiso639-1en-
item.cerifentitytypePublications-
item.openairetypeArticle-
item.fulltextWith Fulltext-
item.grantfulltextrestricted-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
crisitem.author.deptChair of General Physiology and Biophysics-
crisitem.author.orcid0000-0002-4975-3471-
Appears in Collections:Journal Article
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