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https://biore.bio.bg.ac.rs/handle/123456789/1457| Title: | RecBC promoted repair of bleomycin damage in Escherichia coli | Authors: | Knežević Vukčević, Jelena Simić, D. |
Keywords: | bleomycin;repair of DNA strand breaks;recombination deficiency | Issue Date: | 1-Jan-1991 | Journal: | Biochimie | Abstract: | The repair response of Escherichia coli K-12 to bleomycin was examined in Rec- mutants showing differential sensitivity to this agent. Sedimentation analysis of the cellular DNA showed incision after bleomycin treatment. The subsequent reformation of the DNA, found in the wild-type and the recD mutant, was abolished in the recB and delayed in the recF and recBC sbcB mutants. The bleomycin-induced SOS response was reduced in strains containing recB or recBC sbsB mutations. It is suggested that the RecBCD pathway has the main role in the efficient repair of bleomycin-induced DNA damage. © 1991. |
URI: | https://biore.bio.bg.ac.rs/handle/123456789/1457 | ISSN: | 0300-9084 | DOI: | 10.1016/0300-9084(91)90118-K |
| Appears in Collections: | Journal Article |
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