Please use this identifier to cite or link to this item: https://biore.bio.bg.ac.rs/handle/123456789/1086
Title: Immunolocalization of ecto-nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) in the rat forebrain
Authors: Bjelobaba, Ivana
Nedeljković, Nadežda 
Subasic, Sanja 
Lavrnja, Irena
Pekovic, Sanja
Stojkov, Danijela
Rakic, Ljubisav
Stojiljkovic, Mirjana
Keywords: ATP-dependent processes;Brain;Ecto-nucleotide pyrophosphatase/phosphodiesterase;Immunohistochemistry;NPP1
Issue Date: 20-Nov-2006
Journal: Brain Research
Abstract: 
Immunohistochemical study was performed to determine distribution of ecto-nucleotide pyrophosphatase/phosphodiesterase1 (NPP1) in adult rat forebrain. The study revealed widespread distribution of NPP1 in rat forebrain, yet with regional differences in the expression pattern and abundance. Strong NPP1 immunoreaction was detected in pyramidal cell layer of cerebral cortex and hippocampus, and in the midline regions of hypothalamus and thalamus. In many immunopositive forebrain areas, NPP1 was mainly localized at neuronal cell bodies. However, prominent immunoreaction was also detected at ependymal cells, tanycytes, endothelial cells of the capillaries and cells of the choroid plexus, suggesting that NPP1 could be involved in some highly specialized transport process. © 2006 Elsevier B.V. All rights reserved.
URI: https://biore.bio.bg.ac.rs/handle/123456789/1086
ISSN: 0006-8993
DOI: 10.1016/j.brainres.2006.08.114
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