Please use this identifier to cite or link to this item: https://biore.bio.bg.ac.rs/handle/123456789/70
Title: Vasopressin modulates hypothalamo-pituitary activity by paracrine action during acute and chronic immobilization stress in rats
Authors: Lakić, Iva 
Vujović, Predrag 
Jasnić, Nebojša 
Đurašević, Siniša 
Cvijić, Gordana
Keywords: CRH;Hypothalamus;Immobilization stress;Pituitary;Rat;Vasopressin
Issue Date: 11-Aug-2011
Journal: Archives of Biological Sciences
Abstract: 
The aim of the study was to examine changes in corticotropin releasing hormone (CRH), vasopressin (VP), adrenocorticotropin (ACTH) as well as VP3 receptor protein concentration in the hypothalamus and the pituitary of rats exposed to acute (3 h) and chronically repeated (3 h daily for 7 days) immobilization stress. Our results show that, unlike the increase in ACTH, there were no changes in serum VP despite the significant changes in this hormone and its receptor concentrations in the hypothalamus and pituitary (HP). This suggests that VP regulates HP activity by predominantly acting in a paracrine manner under the examined stress condition.
URI: https://biore.bio.bg.ac.rs/handle/123456789/70
ISSN: 0354-4664
DOI: 10.2298/ABS1103579L
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