Please use this identifier to cite or link to this item: https://biore.bio.bg.ac.rs/handle/123456789/6236
Title: Defining the ferroptotic phenotype of beta cells in type 1 diabetes and its inhibition as a potential antidiabetic strategy
Authors: Markelić, Milica 
Stancic, Ana
Saksida, Tamara
Grigorov, Ilijana
Micanovic, Dragica
Veličković, Ksenija 
Martinovic, Vesna
Savic, Nevena
Gudelj, Andjelija
Otasevic, Vesna
Keywords: diabetes;ferroptosis;ferroptosis inhibitor;ferrostatin-1;β-cell death
Issue Date: 3-Aug-2023
Rank: M21
Publisher: Frontiers
Project: Serbian Science and Diaspora Collaboration Program: Knowledge Exchange Vouchers “Ferroptosis in the β-cells death: a possible strategy for diabetes treatment”, acronym: BetFeSis - Science Fund of the Republic of Serbia
Project of the Ministry of Science, Technological Development and Innovation of Republic of Serbia
Journal: Frontiers in Endocrinology
Volume: 14
Start page: 1227498
Abstract: 
Recently, the involvement of ferroptotic cell death in the reduction of β-cell mass in diabetes has been demonstrated. To elucidate the mechanisms of β-cell ferroptosis and potential antidiabetic effects of the ferroptosis inhibitor ferrostatin-1 (Fer-1) in vivo, a mouse model of type 1 diabetes (T1D) was used.
URI: https://biore.bio.bg.ac.rs/handle/123456789/6236
ISSN: 1664-2392
DOI: 10.3389/fendo.2023.1227498
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