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Title: | The effect of the Satureja montana ethanol extract on the morphological changes of erythrocytes | Authors: | Marin, Marija Branković, Snežana |
Keywords: | Winter savory;;Plant extract;;Antioxidant activity;;Blood cells. | Issue Date: | 2023 | Rank: | M23 | Publisher: | Institut za botaniku i botaničku baštu "Jevremovac", Biološki fakultet | Journal: | Botanica Serbica | Volume: | 47 | Issue: | 1 | Start page: | 87 | End page: | 92 | Abstract: | The present study investigated the antioxidant activity of ethanol extracts of the leaves of Satureja montana and their influence on the membrane stability of eryth- rocytes ex vivo. The ethanol extracts showed a very potent antioxidant activity of EC50 = 0.055mg/ml. Rat blood samples were treated with 96% ethanol extracts in different concentrations of 100 μg/ml, 200 μg/ml, and 300 μg/ml, and morphological analyses were carried out. The results showed significant differences in the shape of the erythrocytes incubated with higher extract concentrations. Considerable morphological changes were observed at a concentration of 200 μg/ml which was characterised by the highest percentage of stomatocytes, while the highest percentage of echinocyte formation was observed at a concentration of 300 μg/ml. The results of this investigation indicated that the ethanol extracts of S. montana exhibited a possible protective effect on the membrane stability of erythrocytes. |
URI: | https://biore.bio.bg.ac.rs/handle/123456789/6051 | DOI: | 10.2298/BOTSERB2301087M |
Appears in Collections: | Journal Article |
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