Please use this identifier to cite or link to this item: https://biore.bio.bg.ac.rs/handle/123456789/6051
Title: The effect of the Satureja montana ethanol extract on the morphological changes of erythrocytes
Authors: Marin, Marija 
Branković, Snežana
Keywords: Winter savory;;Plant extract;;Antioxidant activity;;Blood cells.
Issue Date: 2023
Rank: M23
Publisher: Institut za botaniku i botaničku baštu "Jevremovac", Biološki fakultet
Journal: Botanica Serbica
Volume: 47
Issue: 1
Start page: 87
End page: 92
Abstract: 
The present study investigated the antioxidant activity of ethanol extracts of the leaves of Satureja montana and their influence on the membrane stability of eryth- rocytes ex vivo. The ethanol extracts showed a very potent antioxidant activity of EC50 = 0.055mg/ml. Rat blood samples were treated with 96% ethanol extracts in different concentrations of 100 μg/ml, 200 μg/ml, and 300 μg/ml, and morphological analyses were carried out. The results showed significant differences in the
shape of the erythrocytes incubated with higher extract concentrations. Considerable morphological changes were observed at a concentration of 200 μg/ml which was characterised by the highest percentage of stomatocytes, while the highest percentage of echinocyte formation was observed at a concentration of 300 μg/ml.
The results of this investigation indicated that the ethanol extracts of S. montana exhibited a possible protective effect on the membrane stability of erythrocytes.
URI: https://biore.bio.bg.ac.rs/handle/123456789/6051
DOI: 10.2298/BOTSERB2301087M
Appears in Collections:Journal Article

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