Please use this identifier to cite or link to this item: https://biore.bio.bg.ac.rs/handle/123456789/48
Title: Influence of vitamin C supplementation on the oxidative status of rat liver
Authors: Đurašević, Siniša 
Đorđević, Jelena 
Drenča, Tamara
Jasnić, Nebojša 
Cvijić, Gordana
Keywords: Antioxidative protection;Liver;Rats;Vitamin C
Issue Date: 15-Oct-2008
Journal: Archives of Biological Sciences
Abstract: 
Rats have the ability to synthesize vitamin C in the liver. In the present work, we tested whether its additional intake improves antioxidative protection of the tissue. Thus, we studied the liver's oxidative status in rats given two supplements of ascorbic acid over a four-week period of time. Our results confirmed that the additional intake of ascorbate improves the liver's antioxidative defense in a dose-dependent manner. The explanation for the disproportion between the ratio of employed doses of vitamin C and their effects on the studied parameters probably lies in the mechanism of tissue accumulation of ascorbate and balance of its alimentary and endogenous availability.
URI: https://biore.bio.bg.ac.rs/handle/123456789/48
ISSN: 0354-4664
DOI: 10.2298/ABS0802169D
Appears in Collections:Journal Article

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