Please use this identifier to cite or link to this item: https://biore.bio.bg.ac.rs/handle/123456789/435
Title: Within-population genetic effects of mtDNA on metabolic rate in Drosophila subobscura
Authors: Novičić, Zorana Kurbalija
Immonen, Elina
Jelić, Mihailo 
Andjelković, Marko
Stamenković Radak, Marina 
Arnqvist, Göran
Keywords: Metabolic rate;Mitochondria;Mitonuclear epistasis;MtDNA;Polymorphism;Selection
Issue Date: 1-Jan-2015
Journal: Journal of Evolutionary Biology
Abstract: 
© 2015 European Society For Evolutionary Biology. A growing body of research supports the view that within-species sequence variation in the mitochondrial genome (mtDNA) is functional, in the sense that it has important phenotypic effects. However, most of this empirical foundation is based on comparisons across populations, and few studies have addressed the functional significance of mtDNA polymorphism within populations. Here, using mitonuclear introgression lines, we assess differences in whole-organism metabolic rate of adult Drosophila subobscura fruit flies carrying either of three different sympatric mtDNA haplotypes. We document sizeable, up to 20%, differences in metabolic rate across these mtDNA haplotypes. Further, these mtDNA effects are to some extent sex specific. We found no significant nuclear or mitonuclear genetic effects on metabolic rate, consistent with a low degree of linkage disequilibrium between mitochondrial and nuclear genes within populations. The fact that mtDNA haplotype variation within a natural population affects metabolic rate, which is a key physiological trait with important effects on life-history traits, adds weight to the emergent view that mtDNA haplotype variation is under natural selection and it revitalizes the question as to what processes act to maintain functional mtDNA polymorphism within populations.
URI: https://biore.bio.bg.ac.rs/handle/123456789/435
ISSN: 1010-061X
DOI: 10.1111/jeb.12565
Appears in Collections:Journal Article

Show full item record

SCOPUSTM   
Citations

41
checked on Nov 4, 2024

Google ScholarTM

Check

Altmetric

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.