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https://biore.bio.bg.ac.rs/handle/123456789/4025| Title: | Lymphocyte glucocorticoid receptor expression level and hormone-binding properties differ between war trauma-exposed men with and without PTSD | Authors: | Matić, Gordana Milutinović, Danijela Vojnović Nestorov, Jelena Elaković, Ivana Jovanović, Sanja Manitašević Perišić, Tatjana Dunđerski, Jadranka Damjanović, Svetozar Knežević, Goran Špirić, Željko Vermetten, Eric Savić, Danka |
Issue Date: | 2013 | Journal: | Progress in Neuro-Psychopharmacology and Biological Psychiatry | Series/Report no.: | 43;238-245 | Abstract: | Posttraumatic stress disorder (PTSD) has been shown to be associated with altered glucocorticoid receptor (GR) activity. We studied the expression and functional properties of the receptor in peripheral blood mononuclear cells (PBMCs) from non-traumatized healthy individuals (healthy controls; n=85), and war trauma-exposed individuals with current PTSD (n=113), with life-time PTSD (n=61) and without PTSD (trauma controls; n=88). The aim of the study was to distinguish the receptor alterations related to PTSD from those related to trauma itself or to resilience to PTSD. |
URI: | https://biore.bio.bg.ac.rs/handle/123456789/4025 | ISSN: | 0278-5846 | DOI: | 10.1016/j.pnpbp.2013.01.005 |
| Appears in Collections: | Journal Article |
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| Matic-PNPBP-2014.pdf | 434.86 kB | Adobe PDF | Request a copy |
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