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Title: | Complete mitogenome data for the Serbian population: the contribution to high-quality forensic databases | Authors: | Davidovic, S. Malyarchuk, B. Grzybowski, T. Aleksic, J. M. Derenko, M. Litvinov, A. Rogalla-Ładniak, U. Stevanović, Milena Kovacevic-Grujicic, N. |
Issue Date: | 6-Jun-2020 | Rank: | M21 | Journal: | International Journal of Legal Medicine | Series/Report no.: | 134;1581–1590 | Abstract: | Mitochondrial genome (mtDNA) is a valuable resource in resolving various human forensic casework. The usage of variability of complete mtDNA genomes increases their discriminatory power to the maximum and enables ultimate resolution of distinct maternal lineages. However, their wider employment in forensic casework is nowadays limited by the lack of appropriate reference database. In order to fill in the gap in the reference data, which, considering Slavic-speaking populations, currently comprises only mitogenomes of East and West Slavs, we present mitogenome data for 226 Serbians, representatives of South Slavs from the Balkan Peninsula. We found 143 (sub)haplogroups among which West Eurasian ones were dominant. The percentage of unique haplotypes was 85%, and the random match probability was as low as 0.53%. We support previous findings on both high levels of genetic diversity in the Serbian population and patterns of genetic differentiation among this and ten studied European populations. However, our high-resolution data supported more pronounced genetic differentiation among Serbians and two Slavic populations (Russians and Poles) as well as expansion of the Serbian population after the Last Glacial Maximum and during the Migration period (fourth to ninth century A.D.), as inferred from the Bayesian skyline analysis. Phylogenetic analysis of haplotypes found in Serbians contributed towards the improvement of the worldwide mtDNA phylogeny, which is essential for the interpretation of the mtDNA casework. |
URI: | https://biore.bio.bg.ac.rs/handle/123456789/3607 | DOI: | 10.1007/s00414-020-02324-x |
Appears in Collections: | Journal Article |
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