Please use this identifier to cite or link to this item: https://biore.bio.bg.ac.rs/handle/123456789/33
Title: Beneficial Effect of Virgin Coconut Oil on Alloxan-Induced Diabetes and Microbiota Composition in Rats
Authors: Đurašević, Siniša 
Bojić, Svetlana
Nikolić, Biljana 
Dimkić, Ivica 
Todorović, Zoran
Đorđević, Jelena 
Mitić Ćulafić, Dragana 
Keywords: 16S rRNA gene sequencing;Alpha diversity;Beta diversity;Microbiota;Type 2 diabetes
Issue Date: 1-Dec-2018
Rank: M21
Publisher: Springer-Verlag Dordrecht
Journal: Plant Foods for Human Nutrition
Volume: 73
Issue: 4
Start page: 295
End page: 301
Abstract: 
The gut microbiota is composed of a diverse population of obligate and facultative anaerobic microorganisms which are shown to influence host metabolism and immune homeostasis. This study investigated the effects of virgin coconut oil on the weekly fasting glycaemia, daily food and water intake and weekly body mass gain over 16 weeks, as well as the changes in composition of gut microbiota in both non-diabetic and alloxan-induced diabetic rats. Although the intake of virgin coconut oil did not decrease the diabetes-induced hyperglycemia, it affected the secondary parameters, such as food and water intake and average body mass gain. Furthermore, its potential to positively affect the fecal microbiome was proved, since it significantly increased the abundance of probiotic bacteria, such as Lactobacillus, Allobaculum and Bifidobacterium species.
URI: https://biore.bio.bg.ac.rs/handle/123456789/33
ISSN: 0921-9668
DOI: 10.1007/s11130-018-0689-7
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