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Title: | In vitro radioprotective activity of the bryozoan Hyalinella punctata | Authors: | Pejin, Boris Stanimirović, Bojana Đorđević, Neda Hegediš, Aleksandar Karaman, Ivo Horvatović, Mladen Radotić, Ksenija |
Keywords: | Extract;Ionising radiation;Lymphocytes;Plumatellidae | Issue Date: | 2013 | Journal: | Asian Journal of Chemistry | Abstract: | The objective of the present study was in vitro evaluation of radioprotective activity of the freshwater bryozoan Hyalinella punctata on cultured human peripheral blood lymphocytes after irradiation with 2 Gy of 60Co g-rays. Since its water extract at concentration 0.001 mg/ mL reduced the incidence of radiation-induced micronuclei for almost 30 %, it could be considered as a promising source of new natural products with the aforementioned activity. Both the content of sulphur (1.17 %), determined by gravimetric method and infrared absorption frequences (76 % similarity with those of bacitracin) of the investigated extract indicate the presence of organic sulphur compound(s) such as cyclic peptides and polypeptides which might be responsible for the observed radioprotection. |
URI: | https://biore.bio.bg.ac.rs/handle/123456789/2917 | ISSN: | 0970-7077 |
Appears in Collections: | Journal Article |
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