Please use this identifier to cite or link to this item: https://biore.bio.bg.ac.rs/handle/123456789/239
Title: The activities of antioxidant enzymes and monoamine oxidase and uncoupling protein 1 content in brown fat of hypo- and hyperthyroid rats
Authors: Petrović, Nataša
Cvijić, Gordana
Đorđević, Jelena 
Davidović, Vukosava
Keywords: Antioxidant enzymes;Brown fat;Monoamine oxidase;Thyroid hormones;UCP1
Issue Date: 1-Jan-2005
Journal: Annals of the New York Academy of Sciences
Abstract: 
We have studied the activities of antioxidant enzymes (AOE), namely, copper-zinc superoxide dismutase (CuZnSOD), manganese superoxide dismutase (MnSOD), and catalase (CAT), and the activity of catecholamine-degrading enzyme monoamine oxidase (MAO) and uncoupling protein 1 (UCP1) content in brown fat (BF) of hypo- and hyperthyroid rats. We found that hypothyroidism decreased BF UCP1 content and increased MAO, MnSOD, and CAT activities. T3 increased UCP1 content and MnSOD activity and decreased CuZnSOD, MAO, and CAT activities, while T4 significantly altered (decreased) only CAT activity. This study shows that UCP1 content and MAO and AOE activities in rat BF are notably affected by changed thyroid status.
URI: https://biore.bio.bg.ac.rs/handle/123456789/239
ISSN: 0077-8923
DOI: 10.1196/annals.1327.082
Appears in Collections:Journal Article

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