Please use this identifier to cite or link to this item: https://biore.bio.bg.ac.rs/handle/123456789/1430
Title: The effect of essential oil of basil (Ocimum basilicum L.) on UV-induced mutagenesis in Escherichia coli and Saccharomyces cerevisiae
Authors: Stanojević, Jasna
Berić, Tanja 
Opačić, Biljana
Vuković Gačić, Branka 
Simić, Draga
Knežević Vukčević, Jelena 
Keywords: Antimutagenesis;UV-irradiation;Saccharomyces cerevisiae;Escherichia. Coli;Basil oil
Issue Date: 15-Oct-2008
Journal: Archives of Biological Sciences
Abstract: 
The antimutagenic potential of essential oil (EO) of basil (Ocimum basilicum L.) and its major constituent linalool were studied with the E. coli K12 and S. cerevisiae D7 assays. In the E. coli assay, EO and linalool inhibited UV-induced mutagenesis in a repair-proficient strain, but had no effect on spontaneous mutagenesis in repair-proficient, nucleotide excision repair-deficient, and mismatch-deficient strains. By testing participation of different mechanisms involved in antimutagenesis, it was concluded that the antimutagenic effect against UV-induced mutagenesis involved decrease of protein synthesis and cell proliferation which led to increased efficiency of nucleotide excision repair. An antimutagenic effect of basil derivatives in S. cerevisiae was not detected.
URI: https://biore.bio.bg.ac.rs/handle/123456789/1430
ISSN: 0354-4664
DOI: 10.2298/ABS0801093S
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