Please use this identifier to cite or link to this item: https://biore.bio.bg.ac.rs/handle/123456789/1278
Title: Evaluation of antioxidant activity of Melittis melissophyllum L. extracts
Authors: Grujić, Slavica 
Stojanović, Gordana
Mitić, Violeta
Stankov-Jovanović, Vesna
Džamić, Ana 
Alimpić Aradski, Ana 
Marin, Petar 
Keywords: ABTS;DPPH;Extracts;Flavonoids;FRAP;Lamiaceae;Melittis melissophyllum;Phenols
Issue Date: 1-Jan-2014
Rank: M23
Journal: Archives of Biological Sciences
Abstract: 
The antioxidant activities of methanol and ethanol (10%, 30%, 50% and 96%) extracts of the aerial parts of Melittis melissophyllum L. were determined by DPP H, ABTS and FRAP assays. The content of flavonoids and phenols was also investigated. The total phenolic content in the extracts was determined using Folin-Ciocalteu assay; their amounts ranged between 63.5 and 111.7 mg GAeqv/g, while the concentrations of flavonoids were from 7.33 to 56.00 mg Queqv/g. IC50values of the DPP H scavenging effect were from 0.109 to 0.664 mg/mL. The DPP H scavenging effect of the extracts was determined and the obtained IC50values were from 0.109 to 0.664 mg/mL of solution. The values of ABTS radical activity were from 0.45 to 0.89 mg ascorbic acid/g. The FRAP value was within the range 0.160-0.382 mmol Fe/mg. The obtained values were analyzed by means of multivariate analysis, employing a hierarchical cluster analysis and between-groups linkage. The presented results confirmed that M. melissophyllum possesses good antioxidant properties and may serve as a promising source of natural antioxidants.
URI: https://biore.bio.bg.ac.rs/handle/123456789/1278
ISSN: 0354-4664
DOI: 10.2298/ABS1404401G
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