Please use this identifier to cite or link to this item: https://biore.bio.bg.ac.rs/handle/123456789/1262
Title: Plants of the genus Vitis: Phenolic compounds, anticancer properties and clinical relevance
Authors: Salehi, Bahare
Vlaisavljevic, S.
Adetunji, Charles Oluwaseun
Adetunji, Juliana Bunmi
Kregiel, Dorota
Antolak, Hubert
Pawlikowska, Ewelina
Uprety, Y.
Mileski, Ksenija 
Devkota, Hari Prasad
Sharifi-Rad, J.
Das, Gitishree
Patra, Jayanta Kumar
Jugran, Arun Kumar
Segura-Carretero, Antonio
Contreras, María del Mar
Keywords: Anticancer;Phenolic compounds;Proanthocyanidinds;Resveratrol;Vitis
Issue Date: 1-Sep-2019
Rank: M21a
Journal: Trends in Food Science and Technology
Abstract: 
© 2019 Elsevier Ltd Background: Vitis genus comprised about 70 species. Concerning its pharmacological properties, V. vinifera is the most studied one, but there are other species with interest. Scope and approach: Therefore, this review aims to provide an updated overview on bioactive phytochemicals present in food products (grapes and wine) of V. vinifera and other Vitis species, as well as in different underused bioresources (stem, leaves, seeds, wine pomace, etc.). Moreover, due to their promising perspectives in the field of anticancer drug discovery, this bioactivity has been covered as well as the contribution that Vitis phenolic compounds has. Findings and conclusions: Among the plant products reviewed, grape seed extracts was the most investigated at preclinical phase, hence exhibiting a promising potential as anticancer drugs. However, an evidence-based clinical efficacy is still lacking.
URI: https://biore.bio.bg.ac.rs/handle/123456789/1262
ISSN: 0924-2244
DOI: 10.1016/j.tifs.2019.07.042
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