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Title: | 3,5-nonadiyne isolated from the rhizome of Cachrys ferulacea inhibits endogenous nitric oxide release by rat peritoneal macrophages | Authors: | Đoković, Dejan D. Bulatović, Vanja M. Božić, Biljana Kataranovski, Milena V. Zrakić, Tomislav M. Kovačević, Nada N. |
Keywords: | 3,5-nonadiyne;Cachrys ferulacea;Endogenous nitric oxide;Inhibition;Prangos ferulacea | Issue Date: | 1-Jan-2004 | Journal: | Chemical and Pharmaceutical Bulletin | Abstract: | 3,5-Nonadiyne, in vitro, selectively inhibits endogenous nitric oxide release (IC 50 =6.7±0.8 μM) by rat peritoneal macrophages at doses that do not inhibit T cell proliferation. 3,5-Nonadiyne was isolated from root essential oil of Cachrys ferulacea (L.) CALESTANI, synonym Prangos ferulacea (L.) LINDLEY, obtained by hydrodistillation and spectrometricaly identified unambiguously. © 2004 Pharmaceutical Society of Japan. |
URI: | https://biore.bio.bg.ac.rs/handle/123456789/1227 | ISSN: | 0009-2363 | DOI: | 10.1248/cpb.52.853 |
Appears in Collections: | Journal Article |
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