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Title: | Glutathion content, rate of apoptosis, and brown adipose tissue mass in rats exposed to different ambient temperatures | Authors: | Buzadžić, B. Korać, Aleksandra Petrović, V. Korać, Bato |
Keywords: | Apoptosis;Cold adaptation;Glutathione;Interscapular brown adipose tissue;Re-adaptation | Issue Date: | 1-Jan-2004 | Journal: | Journal of Thermal Biology | Abstract: | Amount of glutathione (GSH) in the interscapular brown adipose tissue (IBAT) of cold-adapted (5±1°C), and 1, 3 and 7 days re-adapted (22±1°C) rats were examined.The higher amount of GSH was found in the IBAT of cold-adapted rats compared to control animals (22±1°C).After 1 and 7 days of re-adaptation, the level of GSH was still significantly higher compared to control group.On the third day of re-adaptation, the quantity of GSH in the tissue was significantly lower compared to the cold-adapted group.In cold-adapted animals, intensity of apoptosis in IBAT was lower, whereas in re-adapted animals (3rd and 7th day) it was higher than in control group.This study indicates that GSH depletion is associated with an enhanced apoptosis in IBAT during re-adaptation. © 2004 Elsevier Ltd. All rights reserved. |
URI: | https://biore.bio.bg.ac.rs/handle/123456789/1212 | ISSN: | 0306-4565 | DOI: | 10.1016/j.jtherbio.2004.08.082 |
Appears in Collections: | Journal Article |
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