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https://biore.bio.bg.ac.rs/handle/123456789/7859| Title: | Phosphorylated neurofilament heavy chain in cerebrospinal fluid and plasma as a Nusinersen treatment response marker in childhood-onset SMA individuals from Serbia | Authors: | Brkušanin, Miloš Kosać, Ana Branković-Srećković, Vesna Jovanović, Kristina Perić, Stojan Karanović, Jelena Matijašević Joković, Suzana Garai, Nemanja Pešović, Jovan Nikolić, Dimitrije Stević, Zorica Brajušković, Goran Milić-Rašić, Vedrana Savić-Pavićević, Dušanka |
Keywords: | Nusinersen;antisense oligonucleotide;biomarker;cerebrospinal fluid;phosphorylated neurofilament heavy chain (pNFH);spinal muscular atrophy | Issue Date: | 2024 | Rank: | M21 | Publisher: | National Library of Medicine | Journal: | Frontiers in neurology | Volume: | 15 | Start page: | 1394001 | Abstract: | Biomarkers capable of reflecting disease onset and short- and long-term therapeutic effects in individuals with spinal muscular atrophy (SMA) are still an unmet need and phosphorylated neurofilament heavy chain (pNF-H) holds significant promise. |
URI: | https://biore.bio.bg.ac.rs/handle/123456789/7859 | ISSN: | 1664-2295 | DOI: | 10.3389/fneur.2024.1394001 |
| Appears in Collections: | Journal Article |
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