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https://biore.bio.bg.ac.rs/handle/123456789/490
Title: | Immunoglobulins G from patients with sporadic amyotrophic lateral sclerosis affects cytosolic Ca<sup>2+</sup> homeostasis in cultured rat astrocytes |
Authors: | Milošević, Milena Stenovec, Matja Ž Kreft, Marko Petrušić, Vladimir Stević, Zorica Trkov, Saša Anđus, Pavle Zorec, Robert |
Keywords: | Amyotrophic lateral sclerosis;Astrocytes;Calcium homeostasis;IgG |
Issue Date: | 1-Jan-2013 |
Journal: | Cell Calcium |
Abstract: | Astrocytes are considered essential in the etiopathogenesis of amyotrophic lateral sclerosis (ALS). We have demonstrated previously that immunoglobulins G (IgG) isolated from patients with ALS enhance the mobility of acidic vesicles in cultured astrocytes in a Ca2+-dependent manner. Here we directly examined the impact of purified sporadic ALS IgG on cytosolic [Ca2+] ([Ca2+]i) in astrocytes. Confo... |
URI: | https://biore.bio.bg.ac.rs/handle/123456789/490 |
ISSN: | 0143-4160 |
DOI: | 10.1016/j.ceca.2013.03.005 |
Appears in Collections: | Journal Article |
Files in This Item:
File | Description | Size | Format | Existing users please |
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34 Immunoglobulins-G-from-patients-with-sporadic-amyotrophic-lateral-sclerosis.pdf | 2.3 MB | Adobe PDF | Request a copy |
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