Please use this identifier to cite or link to this item:
https://biore.bio.bg.ac.rs/handle/123456789/428
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Stamenković Radak, Marina | en_US |
dc.contributor.author | Andjelković, Marko | en_US |
dc.date.accessioned | 2019-07-03T10:47:31Z | - |
dc.date.available | 2019-07-03T10:47:31Z | - |
dc.date.issued | 2016-01-01 | - |
dc.identifier.issn | 1821-2158 | - |
dc.identifier.uri | https://biore.bio.bg.ac.rs/handle/123456789/428 | - |
dc.description.abstract | © 2016 Institute of Botany and Botanical Garden Jevremovac, Belgrade. To gain more information on biological effects of plants, particularly herbs used in human medicineand diet, in vitro and in vivo methods have been developed to predict their genotoxicity and/or antigenotoxicity in various test systems. The sex-linked recessive lethal (SLRL) and somaticmutations and recombination (SMART) tests are in vivo assays on D. melanogaster that have beenused to test both mutagenic and antigenotoxic effects of extracts from numerous plant speciesused worldwide. The similarity of metabolic pathways between Drosophila and mammals and theability to activate promutagens make the results of these tests widely applicable. Besides, Drosophilapresents significant orthology with human genes that control cancers, which makes the assays onDrosophila reliable and informative for extrapolations onto humans. | en_US |
dc.relation.ispartof | Botanica Serbica | en_US |
dc.subject | Antimutagenicity | en_US |
dc.subject | Diet | en_US |
dc.subject | Drosophila | en_US |
dc.subject | Genotoxicity | en_US |
dc.subject | Medicinal herbs | en_US |
dc.subject | Plant extracts | en_US |
dc.title | Studying genotoxic and antimutagenic effects of plant extracts in Drosophila test systems | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.5281/zenodo.48854 | - |
dc.identifier.scopus | 2-s2.0-85016563691 | - |
dc.identifier.url | https://api.elsevier.com/content/abstract/scopus_id/85016563691 | - |
item.cerifentitytype | Publications | - |
item.openairetype | Article | - |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.author.dept | Chair of Genetics and Evolution | - |
crisitem.author.orcid | 0000-0002-6937-7282 | - |
Appears in Collections: | Journal Article |
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