Please use this identifier to cite or link to this item: https://biore.bio.bg.ac.rs/handle/123456789/428
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dc.contributor.authorStamenković Radak, Marinaen_US
dc.contributor.authorAndjelković, Markoen_US
dc.date.accessioned2019-07-03T10:47:31Z-
dc.date.available2019-07-03T10:47:31Z-
dc.date.issued2016-01-01-
dc.identifier.issn1821-2158-
dc.identifier.urihttps://biore.bio.bg.ac.rs/handle/123456789/428-
dc.description.abstract© 2016 Institute of Botany and Botanical Garden Jevremovac, Belgrade. To gain more information on biological effects of plants, particularly herbs used in human medicineand diet, in vitro and in vivo methods have been developed to predict their genotoxicity and/or antigenotoxicity in various test systems. The sex-linked recessive lethal (SLRL) and somaticmutations and recombination (SMART) tests are in vivo assays on D. melanogaster that have beenused to test both mutagenic and antigenotoxic effects of extracts from numerous plant speciesused worldwide. The similarity of metabolic pathways between Drosophila and mammals and theability to activate promutagens make the results of these tests widely applicable. Besides, Drosophilapresents significant orthology with human genes that control cancers, which makes the assays onDrosophila reliable and informative for extrapolations onto humans.en_US
dc.relation.ispartofBotanica Serbicaen_US
dc.subjectAntimutagenicityen_US
dc.subjectDieten_US
dc.subjectDrosophilaen_US
dc.subjectGenotoxicityen_US
dc.subjectMedicinal herbsen_US
dc.subjectPlant extractsen_US
dc.titleStudying genotoxic and antimutagenic effects of plant extracts in Drosophila test systemsen_US
dc.typeArticleen_US
dc.identifier.doi10.5281/zenodo.48854-
dc.identifier.scopus2-s2.0-85016563691-
dc.identifier.urlhttps://api.elsevier.com/content/abstract/scopus_id/85016563691-
item.cerifentitytypePublications-
item.openairetypeArticle-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
crisitem.author.deptChair of Genetics and Evolution-
crisitem.author.orcid0000-0002-6937-7282-
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