Please use this identifier to cite or link to this item: https://biore.bio.bg.ac.rs/handle/123456789/2704
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dc.contributor.authorNovakovic, Miroslaven_US
dc.contributor.authorBukvički, Dankaen_US
dc.contributor.authorAndjelkovic, Bobanen_US
dc.contributor.authorIlic-Tomic, Tatjanaen_US
dc.contributor.authorVeljić, Milanen_US
dc.contributor.authorTesevic, Veleen_US
dc.contributor.authorAsakawa, Yoshinorien_US
dc.date.accessioned2019-10-25T11:11:54Z-
dc.date.available2019-10-25T11:11:54Z-
dc.date.issued2019-04-26-
dc.identifier.issn0163-3864-
dc.identifier.urihttps://biore.bio.bg.ac.rs/handle/123456789/2704-
dc.description.abstract© 2019 American Chemical Society and American Society of Pharmacognosy. Seven new bisbibenzyls (1-7) were isolated from the methanol extract of the liverwort Lunularia cruciata along with one previously known bibenzyl and five known bisbibenzyls. The structures of compounds 1-7 were elucidated on the basis of the spectroscopic data. These newly isolated bisbibenzyls may be divided into two groups, the acyclic bisbibenzyls, perrottetins (1-3), and the cyclic analogues, riccardins (4-7). Besides standard perrottetin and riccardin structures (1 and 4, respectively), they contain phenanthrene (3 and 5), dihydrophenanthrene (2), and quinone moieties (6 and 7), rarely found in natural products. The new compounds 3 and 5, as well as the known riccardin G, exhibited cytotoxic activity against the A549 lung cancer cell line with IC50 values of 5.0, 5.0, and 2.5 μM, respectively.en_US
dc.language.isoenen_US
dc.relation.ispartofJournal of Natural Productsen_US
dc.titleCytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciataen_US
dc.typeArticleen_US
dc.identifier.doi10.1021/acs.jnatprod.8b00390-
dc.identifier.pmid30848895-
dc.identifier.scopus2-s2.0-85062828630-
dc.identifier.urlhttps://api.elsevier.com/content/abstract/scopus_id/85062828630-
dc.description.rankM21a-
dc.description.impact4.603-
item.languageiso639-1en-
item.cerifentitytypePublications-
item.openairetypeArticle-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
crisitem.author.deptChair of Plant Morphology and Systematics-
crisitem.author.deptChair of Plant Morphology and Systematics-
crisitem.author.orcid0000-0001-6807-0038-
crisitem.author.orcid0000-0002-1779-1721-
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