Please use this identifier to cite or link to this item:
https://biore.bio.bg.ac.rs/handle/123456789/2653
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ognjanović, Branka I. | en_US |
dc.contributor.author | Marković, Snežana D. | en_US |
dc.contributor.author | Dordević, Nataša Z. | en_US |
dc.contributor.author | Trbojević, Ivana S. | en_US |
dc.contributor.author | Štajn, Andraš Š | en_US |
dc.contributor.author | Saičić, Zorica S. | en_US |
dc.date.accessioned | 2019-10-25T09:55:53Z | - |
dc.date.available | 2019-10-25T09:55:53Z | - |
dc.date.issued | 2010-04 | - |
dc.identifier.issn | 0890-6238 | - |
dc.identifier.uri | https://biore.bio.bg.ac.rs/handle/123456789/2653 | - |
dc.description.abstract | The aim of this study was to investigate the protective role of coenzyme Q10 (CoQ10, 20mg/kg) and Vitamin E (Vit E, 20IU/kg) alone or in combination against cadmium (Cd, 0.4mg/kg) induced lipid peroxidation and changes in antioxidant defense system in the rat testes. The obtained results showed that Cd increased lipid peroxidation in the testes, suggesting that Cd-induced oxidative stress, while CoQ10 and Vit E treatment reversed this change to control values. Acute intoxication with Cd was followed by significantly decreased activity of antioxidant enzymes (SOD, CAT, GSH-Px, GR and GST). Vitamins C and E concentrations also significantly declined in Cd-exposed rat testes. Treatment with CoQ10 and Vit E reversed Cd-induced alterations of antioxidant defense system and significantly prevented Cd-induced testes damage. These results suggest that both CoQ10 and Vit E function as a potent antioxidant in protection of rats testes against the oxidative stress induced by Cd. © 2009 Elsevier Inc. | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Reproductive Toxicology | en_US |
dc.subject | Antioxidant defense system | en_US |
dc.subject | Cadmium | en_US |
dc.subject | Coenzyme Q 10 | en_US |
dc.subject | Lipid peroxidation | en_US |
dc.subject | Oxidative stress | en_US |
dc.subject | Testes | en_US |
dc.subject | Vitamin E | en_US |
dc.title | Cadmium-induced lipid peroxidation and changes in antioxidant defense system in the rat testes: Protective role of coenzyme Q<inf>10</inf> and Vitamin E | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1016/j.reprotox.2009.11.009 | - |
dc.identifier.pmid | 19958828 | - |
dc.identifier.scopus | 2-s2.0-77949570689 | - |
dc.identifier.url | https://api.elsevier.com/content/abstract/scopus_id/77949570689 | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | none | - |
item.openairetype | Article | - |
item.languageiso639-1 | en | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | No Fulltext | - |
crisitem.author.dept | Chair of Algology, Mycology and Lichenology | - |
crisitem.author.orcid | 0000-0002-6715-8422 | - |
Appears in Collections: | Journal Article |
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