Please use this identifier to cite or link to this item: https://biore.bio.bg.ac.rs/handle/123456789/2011
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dc.contributor.authorNasia, Mohammeden_US
dc.contributor.authorRadovanović, Tijanaen_US
dc.contributor.authorKrizmanić, Imreen_US
dc.contributor.authorProkić, Markoen_US
dc.contributor.authorGavrić, Jelenaen_US
dc.contributor.authorDespotović, Svetlanaen_US
dc.contributor.authorGavrilović, Brankaen_US
dc.contributor.authorBorković-Mitić, Slavicaen_US
dc.contributor.authorPavlović, Slađanen_US
dc.contributor.authorSaičić, Zoricaen_US
dc.date.accessioned2019-10-18T11:42:03Z-
dc.date.available2019-10-18T11:42:03Z-
dc.date.issued2018-09-01-
dc.identifier.issn0944-1344-
dc.identifier.urihttps://biore.bio.bg.ac.rs/handle/123456789/2011-
dc.description.abstract© 2018, Springer-Verlag GmbH Germany, part of Springer Nature. Pesticide-induced oxidative stress, as one of mechanism of toxicity, has been a focus of toxicological research. However, there is a lack of data for certain pesticides-oxidative stress effects especially on terrestrial amphibians. This study evaluates the prooxidative effects of orally administered insecticide deltamethrin (DM) in some tissues of the terrestrial toad Bufotes viridis. Toads were randomly divided and assigned to a control group and a test group that was orally exposed to the pesticide (5 mg/kg of body weight/daily) for 21 days. Animals were euthanized from each group on days 7, 14, and 21, and the liver, leg muscle, ventral skin, and gastrointestinal tissue (GIT) were dissected and used for analysis. From battery of investigated antioxidant components, superoxide dismutase (SOD) was the most differentiate parameter in all examined tissues. For the period of prolonged exposure to pesticide, antioxidative strategy of Bufotes viridis was based on SOD utilization in attempt to maintain the oxidative disbalance at acceptable level. The integrated biomarker response (IBR) as the measure of the overall biochemical response to DM exposure revealed that the group exposed for 21 days had the highest response. Our work has offered valuable data ensuring evidence that toads exposed to deltamethrin developed adaptive reactions that were tissue-specific and that DM-generated systemic toxicity was time-dependent. The present work showed that oxidative stress has significant role in pesticide-induced toxicity and contributes to better understanding of ecotoxicological risk in the terrestrial amphibians exposed to DM.en_US
dc.description.sponsorshipMinistry of Education, Science and Technological Development of the Republic of Serbiaen_US
dc.language.isoenen_US
dc.relationMolecular and physiological biomonitoring of aerobic organisms based on the determination of biochemical biomarkers of oxidative stressen_US
dc.relation.ispartofEnvironmental Science and Pollution Researchen_US
dc.subjectBiomarkersen_US
dc.subjectBufotes viridisen_US
dc.subjectChronic exposureen_US
dc.subjectDeltamethrinen_US
dc.subjectOxidative stressen_US
dc.subjectPyrethroiden_US
dc.subjectSublethal exposureen_US
dc.titleProoxidant effects of chronic exposure to deltamethrin in green toad Bufotes viridisen_US
dc.typeArticleen_US
dc.identifier.doi10.1007/s11356-018-2979-x-
dc.identifier.pmid30173389-
dc.identifier.scopus2-s2.0-85053277482-
dc.identifier.urlhttps://api.elsevier.com/content/abstract/scopus_id/85053277482-
dc.description.rankM22-
dc.description.impact4.306-
item.languageiso639-1en-
item.cerifentitytypePublications-
item.openairetypeArticle-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
crisitem.author.deptChair of Morphology, Systematics and Phylogeny of Animals-
crisitem.author.orcid0000-0001-9684-8732-
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