Please use this identifier to cite or link to this item:
https://biore.bio.bg.ac.rs/handle/123456789/1545
DC Field | Value | Language |
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dc.contributor.author | Pejin, Boris | en_US |
dc.contributor.author | Tešanović, Kristina | en_US |
dc.contributor.author | Jakovljević, Dragica | en_US |
dc.contributor.author | Kaišarević, Sonja | en_US |
dc.contributor.author | Šibul, Filip | en_US |
dc.contributor.author | Rašeta, Milena | en_US |
dc.contributor.author | Karaman, Maja | en_US |
dc.date.accessioned | 2019-10-08T11:43:31Z | - |
dc.date.available | 2019-10-08T11:43:31Z | - |
dc.date.issued | 2019-03-04 | - |
dc.identifier.issn | 1478-6419 | - |
dc.identifier.uri | https://biore.bio.bg.ac.rs/handle/123456789/1545 | - |
dc.description.abstract | © 2017, © 2017 Informa UK Limited, trading as Taylor & Francis Group. The polysaccharide (PSH) extracts from the edible mushroom species Coprinus comatus and Coprinellus truncorum were screened in liquid for their acetylcholinesterase inhibitory (AChE) activity. Both extracts were found to display inhibition of the aforementioned enzyme reaching similar IC 50 values of 0.62 ± 0.07 and 0.61 ± 0.03 mg/mL, respectively. According to the means of FTIR spectroscopy, these PSH extracts mostly contained β-glucans. However, the presence of some proteins and polyphenolics as minor ingredients were also detected. Compared with existing literature data for anti-AChE activity of the sugar samples, the findings within this study may be treated as a profound bioactivity. Consequently, this study puts some light on the possible use of the screened macrofungi in the palliative treatment of Alzheimer’s disease. | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Natural Product Research | en_US |
dc.subject | AChE inhibitors of natural origin not belonging to the alkaloids | en_US |
dc.subject | Alzheimer’s disease | en_US |
dc.subject | Mushrooms | en_US |
dc.subject | sugars | en_US |
dc.title | The polysaccharide extracts from the fungi Coprinus comatus and Coprinellus truncorum do exhibit AChE inhibitory activity | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1080/14786419.2017.1405417 | - |
dc.identifier.pmid | 29166776 | - |
dc.identifier.scopus | 2-s2.0-85034782445 | - |
dc.identifier.url | https://api.elsevier.com/content/abstract/scopus_id/85034782445 | - |
dc.description.rank | M22 | - |
dc.description.impact | 2.861 | - |
item.languageiso639-1 | en | - |
item.cerifentitytype | Publications | - |
item.openairetype | Article | - |
item.fulltext | With Fulltext | - |
item.grantfulltext | restricted | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.author.dept | Chair of General Physiology and Biophysics | - |
crisitem.author.orcid | 0000-0002-4975-3471 | - |
Appears in Collections: | Journal Article |
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File | Description | Size | Format | Existing users please |
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The polysaccharide extracts from the fungi.pdf | 819.02 kB | Adobe PDF | Request a copy |
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