Please use this identifier to cite or link to this item: https://biore.bio.bg.ac.rs/handle/123456789/1310
Title: Antifungal and antioxidant activity of Mentha longifolia (L.) Hudson (Lamiaceae) essential oi
Authors: Džamić, Ana 
Soković, Marina
Ristić, Mihailo
Novaković, Miroslav
Grujić, Slavica 
Tešević, Vele
Marin, Petar 
Keywords: Mentha longifolia;essential oil;antifungal;antioxidant activity;DPPH
Issue Date: 10-Jan-2010
Journal: Botanica SERBICA
Abstract: 
The present study describes the antifungal and antioxidant activity of Mentha longifolia (L.) Hudson
essential oil. Th is plant is native to Europe, Central Asia and Australia. It is used as carminative,
stomachic and stimulant and also in aromatherapy. Th e essential oil profi le was determined by GC and
GC-MS. Th e main compounds in the oil were trans-dihydrocarvone (23.64%), piperitone (17.33%) and
cis-dihydrocarvone (15.68%). Minimum inhibitory concentrations (MIC) and minimum fungicidal
concentrations (MFC) were recorded using the microdilution method. Commercial antimicotic
bifonazol was used as a control. Th e concentration of 10 μl/ml showed fungicidal activity against
Aspergillus and Fusarium species, Penicillium funiculosum and Trichoderma viride. Concentration
of 5 μl/ml was effi cient against Trichophyton menthagrophytes and yeast Candida albicans. Th e most
sensitive micromycetes were Cladosporium fulvum, C. cladosporium cladosporioides and Penicillium
ochrochloron where concentration of 2.5 μl/ml was lethal. Th e antioxidant activity of essential oil
was evaluated by means of the 2,2-diphenyl-1-picrylhydrazil (DPPH) radical scavenging method.
Th e essential oil of M. longifolia was able to reduce DPPH radicals into the DPPH-H form, and
this activity was dose-dependent. Th e oil exhibited signifi cant potential for antioxidant activity, and
reduced DPPH to 50% (IC50=0,659 ml/ml of solution).
URI: https://biore.bio.bg.ac.rs/handle/123456789/1310
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