Please use this identifier to cite or link to this item: https://biore.bio.bg.ac.rs/handle/123456789/1207
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dc.contributor.authorMimica-Dukic, Nedaen_US
dc.contributor.authorBugarin, Dušanen_US
dc.contributor.authorGrbovic, Slavenkoen_US
dc.contributor.authorMitić Ćulafić, Draganaen_US
dc.contributor.authorVuković Gačić, Brankaen_US
dc.contributor.authorOrcic, Dejanen_US
dc.contributor.authorJovin, Emilijaen_US
dc.contributor.authorCouladis, Mariaen_US
dc.date.accessioned2019-08-27T13:03:25Z-
dc.date.available2019-08-27T13:03:25Z-
dc.date.issued2010-04-01-
dc.identifier.urihttps://biore.bio.bg.ac.rs/handle/123456789/1207-
dc.description.abstractThe present study describes DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging activity and antimutagenic properties of the essential oil of myrtle (Myrtus communis L.). Plant samples were collected from the two distant localities (southernmost and northern point) of the Montenegro coastline. Chemical profiles of the two samples were evaluated by GC-MS. In both of the samples monoterpenes were found to be the predominant compounds. Among them ?-pinene, linalool, 1,8-cineole, and myrtenyl acetate were the major compounds. Significant differences between the samples were found in the ranges of ?-pinene (14.7%-35.9%) and myrtenyl acetate (5.4%-21.6%). Both oils exhibited moderate DPPH scavenging activity, with IC50 values of 6.24 mg/mL and 5.99 mg/mL. The antimutagenic properties were assayed against spontaneous and t-BOOH-induced mutagenesis in Escherichia coli oxyR mutant IC202, a bacterial strain deficient in removing ROS. Reduction of the spontaneous mutagenesis in presence of myrtle EO was only slight, up to 13% at the highest concentration tested. When the oxidative mutagen was used, EO expressed higher reduction of mutagenesis, in a concentration dependent manner, with statistical significance for effect at the highest concentration tested (28%). Suppression of t-BOOH induced mutagenesis was correlated with the observed scavenging activity. Copyright © 2010 by the authors.en_US
dc.language.isoenen_US
dc.relation.ispartofMoleculesen_US
dc.subjectα-pineneen_US
dc.subject1,8-cineoleen_US
dc.subjectDPPH testaen_US
dc.subjectEssential oilen_US
dc.subjectMutagenesisen_US
dc.subjectMyrtus communis L.en_US
dc.subjectMyrtenyl acetateen_US
dc.titleEssential oil of myrtus communis l. As a potential antioxidant and antimutagenic agentsen_US
dc.typeArticleen_US
dc.identifier.doi10.3390/molecules15042759-
dc.identifier.pmid20428077-
dc.identifier.scopus2-s2.0-77951874989-
dc.identifier.urlhttps://api.elsevier.com/content/abstract/scopus_id/77951874989-
item.languageiso639-1en-
item.cerifentitytypePublications-
item.openairetypeArticle-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
crisitem.author.deptChair of Microbiology-
crisitem.author.deptChair of Microbiology-
crisitem.author.orcid0000-0002-6651-6814-
crisitem.author.orcid0000-0001-8767-1912-
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