Please use this identifier to cite or link to this item: https://biore.bio.bg.ac.rs/handle/123456789/1185
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dc.contributor.authorCimbaljević, Brankoen_US
dc.contributor.authorVasilijević, Anaen_US
dc.contributor.authorCimbaljević, Slavicaen_US
dc.contributor.authorBuzadžić, Biljanaen_US
dc.contributor.authorKorać, Aleksandraen_US
dc.contributor.authorPetrović, Vesnaen_US
dc.contributor.authorJanković, Aleksandraen_US
dc.contributor.authorKorać, Batoen_US
dc.date.accessioned2019-08-16T13:09:31Z-
dc.date.available2019-08-16T13:09:31Z-
dc.date.issued2007-10-01-
dc.identifier.issn0008-4212-
dc.identifier.urihttps://biore.bio.bg.ac.rs/handle/123456789/1185-
dc.description.abstractThis study aimed to investigate the interrelationship of plasma lipid profile, lipid peroxidation, and erythrocyte antioxidative defense in patients with insulin-dependent (IDDM) and non-insulin-dependent (NIDDM) diabetes mellitus. Plasma levels of total cholesterol, triglycerides, and lipid peroxides and the activities of copper, zinc superoxide dismutase (CuZnSOD), catalase, glutathione peroxidase (GSH-Px), as well as the amount of glutathione in erythrocytes, were determined in IDDM, NIDDM, and nondiabetic control subjects. Additionally, morphology of erythrocytes in all subjects was examined. Plasma levels of total cholesterol and triglycerides were significantly increased in NIDDM compared with controls. Also, the lipid peroxide level was higher in NIDDM than in either control or IDDM subjects. CuZnSOD activity in erythrocytes was elevated in NIDDM patients compared with the control. In NIDDM patients, more extensive erythrocyte spherocytosis and echinocytosis compared with both control and IDDM subjects were observed. In contrast with the IDDM group, the observed abnormality in lipid metabolism in NIDDM patients is closely associated with increased lipid peroxidation, changes in antioxidative defense, and erythrocyte morphology. © 2007 NRC.en_US
dc.language.isoenen_US
dc.relation.ispartofCanadian Journal of Physiology and Pharmacologyen_US
dc.subjectAntioxidative defenseen_US
dc.subjectDiabetes mellitusen_US
dc.subjectErythrocytesen_US
dc.subjectLipid profileen_US
dc.subjectReactive oxygen speciesen_US
dc.titleInterrelationship of antioxidative status, lipid peroxidation, and lipid profile in insulin-dependent and non-insulin-dependent diabetic patientsen_US
dc.typeArticleen_US
dc.identifier.doi10.1139/Y07-088-
dc.identifier.pmid18066100-
dc.identifier.scopus2-s2.0-38049011756-
dc.identifier.urlhttps://api.elsevier.com/content/abstract/scopus_id/38049011756-
item.languageiso639-1en-
item.cerifentitytypePublications-
item.openairetypeArticle-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
crisitem.author.deptChair of Cell and Tissue Biology-
crisitem.author.orcid0000-0002-3044-9963-
crisitem.author.orcid0000-0001-5272-579X-
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