Please use this identifier to cite or link to this item: https://biore.bio.bg.ac.rs/handle/123456789/1172
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dc.contributor.authorMacanovic, Biljanaen_US
dc.contributor.authorVucetic, Milicaen_US
dc.contributor.authorJankovic, Aleksandraen_US
dc.contributor.authorStancic, Anaen_US
dc.contributor.authorBuzadzic, Biljanaen_US
dc.contributor.authorGaralejic, Elianaen_US
dc.contributor.authorKorać, Aleksandraen_US
dc.contributor.authorKorać, Batoen_US
dc.contributor.authorOtasevic, Vesnaen_US
dc.date.accessioned2019-08-16T12:12:34Z-
dc.date.available2019-08-16T12:12:34Z-
dc.date.issued2015-01-01-
dc.identifier.issn0278-0240-
dc.identifier.urihttps://biore.bio.bg.ac.rs/handle/123456789/1172-
dc.description.abstractBackground. Semen analysis is the cornerstone in the evaluation of male (in)fertility. However, there are men with normal semen tests but with impaired fertilizing ability, as well as fertile men with poor sperm characteristics. Thus, there is rising interest to find novel parameters that will help to predict and define the functional capacity of spermatozoa. Methods.We examined whether there is a correlation between semen parameters (count, progressive motility, and morphology) and protein expression/activity of antioxidative defense enzymes in seminal plasma from 10 normospermic subjects. Results. Sperm progressive motility was in positive correlation with seminal plasma protein expression of both superoxide dismutase (SOD) isoforms (MnSOD and CuZnSOD) and catalase. Also, positive correlation was observed between sperm count and MnSOD protein expression, as well as between spermmorphology and protein expression of catalase in seminal plasma. In contrast, protein expression of glutathione peroxidase was not in correlation with any sperm parameter, while its activity negatively correlated with sperm morphology and motility. Conclusions.These data suggest that evaluation of protein expression of antioxidative defense enzymes in seminal plasma might be of importance in the evaluation ofmale fertility status and that could be used as an additional biomarker along with classic semen analysis in assessment of semen quality.en_US
dc.language.isoenen_US
dc.relationReactive oxygen and nitrogen species functions in reproduction: possible pharmacological tools to treat human infertilityen_US
dc.relationCOST [BM1203]en_US
dc.relation.ispartofDisease Markersen_US
dc.titleCorrelation between sperm parameters and protein expression of antioxidative defense enzymes in seminal plasma: A pilot studyen_US
dc.typeArticleen_US
dc.identifier.doi10.1155/2015/436236-
dc.identifier.pmid25691806-
dc.identifier.scopus2-s2.0-84933074260-
dc.identifier.urlhttps://api.elsevier.com/content/abstract/scopus_id/84933074260-
dc.description.rankM22en_US
item.languageiso639-1en-
item.cerifentitytypePublications-
item.openairetypeArticle-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
crisitem.author.deptChair of Cell and Tissue Biology-
crisitem.author.orcid0000-0002-3044-9963-
crisitem.author.orcid0000-0001-5272-579X-
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