1. BIOREpository

COMPARATIVE ANALYSIS OF CORTICAL REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION AND SUBCORTICAL DEEP BRAIN STIMULATION ON MOTOR AND NON-MOTOR SYMPTOMS IN AN EXPERIMENTAL MODEL OF PARKINSON’S DISEASE

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Project title
COMPARATIVE ANALYSIS OF CORTICAL REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION AND SUBCORTICAL DEEP BRAIN STIMULATION ON MOTOR AND NON-MOTOR SYMPTOMS IN AN EXPERIMENTAL MODEL OF PARKINSON’S DISEASE
Project Coordinator
Participant Organization(s)
 
Status
In progress
Start date
01-07-2025
Expected Completion
01-07-2026
 
Co-Investigator(s)

Description

Abstract
Parkinson’s disease is a neurodegenerative disorder with motor and non-motor symptoms related to dopaminergic loss. This project compares two innovative neuromodulatory therapies: the non-invasive SAINT protocol and the invasive burst DBS in a 6-OHDA rat model. Using behavioral, neurochemical and synaptic analyses, Serbian and Canadian teams will evaluate their efficacy and mechanisms. This collaboration will pioneer translational insights and optimize PD treatments and therapeutic outcomes.